In 2005 the British government's Health Committee undertook a official report into the influence of the pharmaceutical industry. It stated that "The consequences of lax oversight is that the industry’s influence has expanded and a number of practices have developed which act against the public interest". The practices they list are:
"that clinical trials were not adequately designed – that they could be
designed to show the new drug in the best light – and sometimes fail to indicate the true
effects of a medicine on health outcomes relevant to the patient. We were informed of
several high-profile cases of suppression of trial results. We also heard of selective
publication strategies and ghost-writing. The suppression of negative clinical trial findings
leads to a body of evidence that does not reflect the true risk: benefit profile of the medicine
in question".
The report is interesting see:
http://www.parliament.the-stationery-office.co.uk/pa/cm200405/cmselect/cmhealth/42/42.pdf